[I/O] new format: Zeiss CZI (brightfield and fluorescence, multiple scenes support)
[I/O] new format: Hamamatsu NDPIS (mIF)
[I/O] fix issue with opening certain Roche scans in *.bif format
16 bit rendering and 16 bit histogram (optionally force 8 bit to save memory)
[studio] FL Colocalization App has new mode: segment nuclei and create cell outline by growing nucleus. Select for each marker whether they should be evaluated only in the nucleus, only in the cytoplasm or in both zones.
[studio] IHC Cell Detection App: redone from scratch. More options and better quality results. Support cytoplasmic/membrane markers such as T-cell markers CD3/CD4/CD8.
[studio] FISH HER2/neu App: show additional diagrams / plots
[studio] Mask-by-Color App: now also works with fluorescent slides
[studio] Cell-Cell-Connection App: collect more statistics, incl. #bystanders by cell type and average distance by cell type
new feature: Tiling App and Annotation-Image-Export App can now also create masks that can be used to train segmentation AI models
new feature: force for annotations globally: filled or outline-only
new feature: annotation classes can be tagged. Classes can be hidden or shown by tag.
new feature: list annotations in column in "Slides" table view
new feature: double-click viewer with hand-tool to zoom-in. Double-click again to zoom-out again.
new feature: combine live stain unmixing with masking
new feature: show annotation counts in slide pane (in table-view)
new feature: export annotations from multiple selected slides into csv (via slide pane)
highlight in "Slides" pane, which slides are currently opened
add create/load preset buttons more prominently to classes sidebar
make annotation actions (grow, scale, select, add margins...) accessible from popover in main toolbar
new feature: add toolbar buttons to open previous / next slide in workspace
new feature: fly to previous / next annotation in class
bugfix: vertical coordinate offset in Aperio XML annotation export for slides with non-square pixels (e.g. 3DHistech P1000)
various bugfixes
Version 1.1.0
MICAIA studio release
[studio] new Apps: Mask by Color, Cell-based IHC Scoring, FL Cell Counting, FL Colocalization, FL Spot Counting, FL FISH HER2/neu Scoring, Cell-Cell Connections
[studio] FL Colocalization Plots
new free App: Foreground Detection
Tile Export App: support only exporting tiles that contain foreground (tissue)
improved pen tool: user can now release the mouse while drawing an annotation in order to to rest their finger or to navigate
viewer supports stain-unmixing
new "annotation class changer" tool. This brush changes all existing annotations it touches to the currently selected class.
support Olympus VSI format (brightfield only)
App configurations can now be saved as a prese
support executing analysis batches from *.micbat file
A set of classes including their names and styles can now be saved as a preset
markup opacity can now be changed centrally for all classes at once
the image layer can now be hidden in order to only show the markup
added new more flexible window docking system
when multiple slides are viewed side-by-side, their title is now visible in the tab title
support reading annotations from *.mrxs slides
when a Aperio XML markup file is located next to a slide and has the same base name, it will automatically be loaded
redesigned the annotation class buttons so that it can be more easily selected
bugfix: undo/redo not possible for changing an annotation's class
bugfix: the current class was sometimes reset to the first class
bugfix: slide was marked as having pending changes even when annotation layers were shown/hidden
bugfix: auto-save file was used even when user answered "restore?" prompt with "no"
Fraunhofer Institute for Integrated Circuits IIS